PUGNAc extrapure, 95%

PUGNAc extrapure, 95%
PUGNAc extrapure, 95%
Price And Quantity
  • Milligram/Milligrams
  • 5
  • Milligram/Milligrams
  • 42USD
    Product Specifications
    • 29420090
    • PUGNAc
    • 132489-69-1
    • 95
      Product Description
      PUGNAc is a 1,5-hydroximolactone, acting as an inhibitor of a variety of N-acetylhexosaminidases. It was long thought that increased levels of O-GlcNAc in human cells lead to Type II diabetes. O-GlcNAc levels were artificially raised with PUGNAc, which inhibits O-GlcNAcase, a beta-exo-N-acetylhexosaminidase which cleaves beta-O-linked-N-acetylglucosamine residues from glycoproteins. As a result of this inhibition, a type II diabetic phenotype was observed. Recent pharmacological studies using a more selective O-GlcNAcase inhibitor did not see this effect. However, genetic manipulation of O-GlcNAc levels is consistent with the effects observed by PUGNAc, namely insulin resistance upon elevation of O-GlcNAc levels.
      Trade Information
      • Mumbai International Airport
      • Paypal, Western Union, Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Delivery Point (DP), Days after Acceptance (DA), Cheque, Cash in Advance (CID), Cash Advance (CA), Cash on Delivery (COD), Cash Against Delivery (CAD)
      • 1000 Per Month
      • 5 Days
      • Contact us for information regarding our sample policy
      • Customized.
      • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
      • All India
      • ISO FDA GMP CE
      Related Products

      Send Inquiry
      Amlodipine Besylate

      Send Inquiry
      Acetone Sodium Bisulfite

      Send Inquiry

      Send Inquiry
      Fenoterol Hydrobromide

      Send Inquiry

      Send Inquiry
      right arrow
      left arrow
      Contact Us

      416, Apple Square, Nr. Swastik Plaza, Yogi Chowk  Surat  Gujarat  India  +918037405164
      Phone :+918037405164